Researchers Co-funded by National MS Society Report on New Way to Translate Lab Findings Aimed at Repairing Nerve-Insulating Myelin

With support from the National MS Society, University of Buffalo researchers compared genes for myelin-making cells in mice, rats, and people. Myelin surrounds nerve fibers, and is a target of the immune attack in MS. Strategies for promoting myelin repair sometimes succeed in mice or rats, and then not work in people, so this team used a new software tool to determine whether this was due to fundamental differences between species in the genes that instruct myelin formation. In the process, they identified a protein – GNB4 – that appears…

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